Info

SSRL is a synchrotron facility at SLAC National Accelerator Laboratory, Stanford University (Menlo Park, CA). DOE Office of Science user facility. Provides multiple structural biology beamlines for macromolecular crystallography and SAXS/WAXS. Also home to LCLS (Linac Coherent Light Source), the world’s first hard X-ray free-electron laser.

LCLS connection

LCLS and LCLS-II at SLAC enable serial femtosecond crystallography (SFX), a technique of growing importance for studying protein dynamics and time-resolved crystallography. This connects to DiffUSE’s interest in protein dynamics.

Key Relationships

  • Co-located with LCLS/LCLS-II (XFEL, serial crystallography)
  • DIALS being adapted for XFEL serial crystallography data (via LBNL collaboration)
  • Stanford-SLAC cryo-EM facility also on campus

Funding

  • DOE Office of Science (primary)
  • NIH (structural biology beamlines)

Key Reference

SSRL website: https://www-ssrl.slac.stanford.edu