computational

ETH Zurich / formerly EMBL-EBI

Info

Associate Professor at the Institute of Molecular Systems Biology (IMSB), ETH Zurich (joined January 2022; previously at EMBL-EBI). His group develops computational methods to study the evolution and function of post-translational modifications (PTMs), reconstructing kinase signaling networks, studying PTM dynamics in disease, and connecting genotype to phenotype. Expertise in computational proteomics, phosphoproteomics, and large-scale data integration.

DiffUSE relevance

Beltrao’s work on structural consequences of PTMs and mutations at proteome scale is relevant to DiffUSE’s interest in how protein conformational dynamics change in response to perturbations. His computational methods for predicting the structural impact of genetic variants could be applied to understanding how mutations or modifications alter diffuse scattering patterns.

Key Relationships

  • ETH Zurich IMSB — current position
  • EMBL-EBI — previous group leader (Beltrao Group); connection to structural bioinformatics community
  • Swiss Institute of Bioinformatics (SIB)
  • PTM / phosphoproteomics computational community

Sources