mx cryo-em computational software-dev
University of Hamburg / Excellence Cluster CUI
Info
Group leader in the Excellence Cluster CUI (Advanced Imaging of Matter) at the Institute of Nanostructures and Solid State Physics, University of Hamburg. Developer of AUSPEX (diffraction diagnostics tool for X-ray data) and HARUSPEX (neural network for automatic secondary structure annotation of cryo-EM maps). Led the global Coronavirus Structural Task Force during the COVID-19 pandemic, which coordinated re-processing and validation of SARS-CoV-2-related structures.
Handoff context
Thorn is one of the most visible current-generation CCP4-adjacent figures: she trained under George Sheldrick (SHELX lineage) at Göttingen, contributed to SHELX / ANODE / PHASER historically, and now runs an independent group applying ML to validation. The Coronavirus Structural Task Force established her as a community organizer.
Key Relationships
- George Sheldrick (Göttingen) — PhD supervisor (2011)
- SHELX, ANODE, Phaser — historical contributions
- AUSPEX / HARUSPEX — principal developer
- Coronavirus Structural Task Force — leader
- CCP4 developer/contributor
- Hamburg structural biology community alongside Helen Ginn at DESY
Sources
- CCP4 People page: https://www.ccp4.ac.uk/about/people/
- Thorn Lab: https://thorn-lab.com
- Coronavirus Structural Task Force: https://github.com/thorn-lab/coronavirus_structural_task_force