Info
SerialEM is the dominant software for automated data acquisition on transmission electron microscopes. Developed by David Mastronarde at the University of Colorado Boulder. Used for both single-particle cryo-EM and electron tomography. Free for academic use.
People
| Name | Role | Affiliation |
|---|---|---|
| David Mastronarde | Developer / maintainer | University of Colorado Boulder |
Key Relationships
- Controls data collection on most cryo-EM microscopes worldwide
- Feeds data into RELION, cryoSPARC, EMAN2 processing pipelines
- Competes with EPU (Thermo Fisher proprietary) for automated acquisition
Key Reference
Mastronarde, J Struct Biol 152, 36-51 (2005)