mx cryo-em computational software-dev
Duke University / Richardson Lab / PHENIX Consortium
Info
Postdoctoral Associate in the Richardson Lab at Duke University, Department of Biochemistry. Core developer of Reduce (hydrogen placement for all-atom contact analysis) and CaBLAM (CA/CB-based model validation, designed specifically for low-resolution cryo-EM structures where Ramachandran and rotamer analysis fail). First author of the 2018 MolProbity update paper.
Handoff context
Williams is the current Richardson Lab lead on cryo-EM-era model validation, picking up the MolProbity tradition for a new regime where structures are often solved at resolutions where classical validation breaks down.
Key Relationships
- Jane S. Richardson and David C. Richardson — PIs at Duke
- Vincent Chen — Richardson Lab senior colleague
- W. Bryan Arendall, III — Richardson Lab colleague and XVTF member
- MolProbity — core developer; first author 2018 update
- CaBLAM — principal author; addresses cryo-EM low-resolution validation
- PHENIX Consortium — Duke site
Sources
- PHENIX team page: https://phenix-online.org/people
- MolProbity 2018 update (Williams et al.): https://onlinelibrary.wiley.com/doi/full/10.1002/pro.3330