leader mx cryo-em computational software-dev
MRC Laboratory of Molecular Biology / MRC-LMB
Info
Group leader in the Structural Studies Division at the MRC-LMB, Cambridge. Principal author of REFMAC5, the maximum-likelihood macromolecular refinement program in CCP4 used across MX and (more recently) cryo-EM map refinement. REFMAC has been one of the two dominant refinement packages worldwide (alongside phenix.refine).
Key Relationships
- CCP4 — REFMAC5 is the flagship CCP4 refinement tool
- MRC Laboratory of Molecular Biology — group leader
- Paul Emsley — MRC-LMB colleague; REFMAC integrates with Coot
- Ligand Validation Workshop 2015 attendee
Sources
- 2016 LVW paper: https://www.cell.com/structure/fulltext/S0969-2126(16)00076-9