leader nmr computational software-dev pi wwpdb archive-lead
BMRB / University of Connecticut
Info
Professor in the Department of Molecular Biology and Biophysics at UConn Health (Farmington, CT). Serves as Director of the Biological Magnetic Resonance Data Bank (BMRB), the NMR archive within the wwPDB consortium; Director of the Gregory P. Mullen NMR Structural Biology Facility; Director of the National Center for Biomolecular NMR Data Processing and Analysis (NMRbox.org); and Director of the Network for Advanced NMR (NAN). NMRbox is a freely available virtualisation platform providing hundreds of NMR software packages preconfigured in a single environment - a response to fragmentation in biomolecular NMR tooling.
wwPDB role
Principal Investigator for BMRB, the NMR member body of the wwPDB. BMRB was co-founded at the University of Wisconsin Madison in 1988 by John Markley (founding PI) and Eldon Ulrich (founding operational director). Hoch took over and oversaw the archive’s relocation to UConn Health, Farmington.
Affiliations
- UConn Health — Professor, Department of Molecular Biology and Biophysics
- BMRB — Director
- Gregory P. Mullen NMR Structural Biology Facility — Director
- NMRbox (National Center for Biomolecular NMR Data Processing and Analysis) — Director
- Network for Advanced NMR (NAN) — Director
Training
- PhD in Physical Chemistry, Harvard University
Committees & service
- wwPDB — Principal Investigator (BMRB)
Key Relationships
- Succeeded the founding Wisconsin-era leadership of John Markley and Eldon Ulrich when the archive transitioned to UConn Health
- NMR software community connections: Michael R. Gryk, Mark Maciejewski, Kumaran Baskaran, Dmitri Maziuk
Software / Infrastructure
- NMRbox — virtualised platform with preconfigured biomolecular NMR software; developed with Michael R. Gryk and collaborators
- BMRB — NMR data archive
Sources
- UConn Health faculty directory: https://facultydirectory.uchc.edu/profile?profileId=hoch-jeffrey
- Meet the Researcher feature: https://today.uconn.edu/2021/01/meet-the-researcher-jeff-hoch-school-of-medicine/
- NMRbox paper (J Biomol NMR 2017): https://pubmed.ncbi.nlm.nih.gov/28445744/
- wwPDB 2025 Advisory Committee report: https://cdn.rcsb.org/wwpdb/docs/about/advisory/wwpdbac2025-report.pdf