aliases:
- Biological Magnetic Resonance Data Bank
- Biological Magnetic Resonance Data Bank (BMRB)
- BioMagResBank
Info
BMRB is the international open data repository for biomolecular NMR data. Founded in 1988 by John Markley and Eldon Ulrich at the University of Wisconsin-Madison. Now based at UConn Health (Farmington, CT). Partner site BMRBj operated by Osaka University / PDBj. BMRB became a core member of the wwPDB in 2007. The archive contains >10.8 million assigned chemical shifts across >15,000 studies.
Key Relationships
- Core Archive member of wwPDB
- Partner site BMRBj at PDBj (processes ~10% of entries)
- Mirror site at CERM, University of Florence, Italy
- Close collaboration with NMRbox (NMR software/HPC platform, also at UConn Health)
- Collaborates with CCPN, RCSB PDB, PDBe, EMDB
- Depositions linked to PDB, European Nucleotide Archive, NCBI, UniProt
People
| Name | Title | Affiliation |
|---|---|---|
| Jeffrey Hoch | PI / Director | UConn Health |
| Kumaran Baskaran | Assistant Scientist | UConn Health |
| Hamid Eghbalnia | Staff Data Scientist | UConn Health |
| Michael R. Gryk | Staff | UConn Health |
| Jonathan R. Wedell | Staff | UConn Health |
| Dmitri Maziuk | Staff | UConn Health |
| Colin Wilburn | Staff | UConn Health |
| Harrison Burr | Staff | UConn Health |
| John Chin | Staff | UConn Health |
| Hongyang Yao | Staff | UConn Health |
BMRBj (Japan)
| Name | Affiliation |
|---|---|
| Toshimichi Fujiwara | Osaka University |
| Masashi Yokochi | Osaka University |
| Takeshi Iwata | Osaka University |
| Yohei Miyanoiri | Osaka University |
| Chojiro Kojima | Yokohama National University |
Founders
| Name | Role | Affiliation |
|---|---|---|
| John Markley | Founder (1988), former PI | University of Wisconsin-Madison |
| Eldon Ulrich | Co-founder | University of Wisconsin-Madison |
Funding
Originally housed at University of Wisconsin-Madison with continuous support from NLM (NIH) since 1990 in 5-year grants. NLM phased out external center funding; last renewal was 2009. BMRB faced a funding crisis around 2014 (covered by Nature Structural & Molecular Biology editorial). Now supported by NIGMS at UConn Health.
Funding note
The 2012 Nature NSMB editorial highlighted BMRB’s precarious funding situation. The transition from UW-Madison to UConn Health and shift from NLM to NIGMS was a major governance event in this space.
Governance
- Jeffrey Hoch is a wwPDB Principal Investigator
- BMRB is represented on the wwPDB Advisory Committee by Hari Arthanari (Co-Chair) and Christina Redfield